Cdx-110

[Enviro Girl]

Is this the 'Smart' Bomb Cancer drug I'm hearing sudden media fuss about? Timing seems funny...
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News Article

NEW YORK—Pfizer Inc. has struck a deal with DxS, a wholly owned subsidiary of QIAGEN, for a companion diagnostic test kit that will be used alongside a new brain tumor drug.

That drug, Pfizer’s PF-04948568 (CDX-110), is an immunotherapy vaccine for treating newly diagnosed glioblastoma multiforme (GBM), the most common malignant primary brain tumor in adults—occurring in around 25,000 patients worldwide each year. CDX-110 is a peptide vaccine which targets the tumor-specific Epidermal Growth Factor Receptor variant III (EGFRvIII), a mutated form of the epidermal growth factor receptor that is only present in cancer cells and occurs in 25 to 40 percent of GBM tumors.

Pfizer and Celldex Therapeutics Inc. signed an agreement in 2008 granting Pfizer an exclusive worldwide license to CDX-110, which is currently in Phase II clinical development. Pfizer is also exploring lifecycle opportunities for CDX-110 in other tumor types expressing the EGFRvIII mutation.

The diagnostic being developed in the Pfizer-DxS deal will be a real-time PCR assay used to detect EGFRvIII RNA in tumor tissue. The EGFRvIII companion diagnostic will be developed and manufactured at QIAGEN’s Center of Excellence for Companion Diagnostics in Manchester, U.K. The assay is designed to offer a simple workflow, which supports its clinical utility in routine mutation testing.

In a statement, Pfizer said that by developing CDX-110, its oncology business unit “continues to show its commitment to developing the right drug for each patient.”

“We look forward to collaborating with QIAGEN’s DxS unit in the development of this important diagnostic tool that could potentially help physicians better define the most appropriate treatment for patients who suffer from glioblastoma multiforme,” notes Garry Nicholson, president and general manager of Pfizer’s oncology business unit.

Pfizer is the latest global pharmaceutical giant to sign an agreement of this nature with DxS, following similar deals with companies including AstraZeneca and Amgen.
Founded in 2001, DsX is making a name for itself in the field of personalized medicine and has a healthy pipeline of deals, says co-founder Dr. Steve Little, who is also vice president of personalized healthcare for QIAGEN. DxS is also looking to develop kits for use on heart patients as well as those suffering from cancer, he adds.

“QIAGEN is aligned to deliver companion diagnostics to our pharmaceutical partners, and this deal is further evidence of our commitment to develop our scientific and operational capabilities to help select the right patient for the right medicine,” Little says.

Financial terms of the diagnostic agreement were not disclosed.

[Kritters]

Baking soda destroys tumors of all kinds in days. Cancer is a fungus - the book by Dr. T. Simoncini

YouTube - ABBA Money Money Money

[ChatCat]

Can the American economy handle a cure for cancer?
Cut, burn and poison methods are generating trillions by now.

Don't get me going as you can see it doesn't take much for me when it comes to Big Pharma.

How much ya wanna bet that this one will be supress just like the rest of them. It barely made any news.



"The tumour literally liquefies.

"There is a rapid knock-down of the tumour, it disintegrates within 24 hours and we have a rapid healing response.


Possible cancer cure found in blushwood shrub | Courier Mail

[Baraka Obam]

The knights that say Nee are also looking for it, hmmm they say the correct situatin is 7 years away with this shubbery!!!!

YouTube - The Knights Who say Nee!

[Enviro Girl]

Have you guys been hearing about this when I was off Nancy Drew-ing the last few years?!
I used to love CNN, lost a lot of respect for them due to poor coverage of Morgellon's. This story's getting a big push there this week w/Sanjay Gupta. I think this site is prolly being watched, so the timing this week seems funny if this the first we're hearing of it. (?!)
Heard cancer 'smart b' and almost fell out of my armchair!
CC: I'm sure they aren't happy to have to bring this news yet, ya know they wanted to keep sodomizing sick people at max cost, as long as they could. TFB. (looked like in my quick search, stories about CDX-110 since at least 2005? That's when the agrobac tech patent was shared and settled in court. Fits in w/my Morgie timeline o corruption perfectly!)
This name is kinda scary though, maybe they will put a more appealing name on it before they start marketing. So they can make commercials of ppl running through fields w/flowers and then list 30 seconds worth of AWFUL side effects like a$$-leakage, your head falls off, ya fart out your nose, etc.,. This to me sounds like being one of the first to get the new version of a Microsoft platform - prolly some bugs to be worked out, wouldn't want to be one of the first to try it, no thanks...
Now that they've got their disgusting greedy cancer patents in place, it BETTER be time to help Morgies, officially.

[Katinka]

Originally Posted by Enviro Girl

So they can make commercials of ppl running through fields w/flowers and then list 30 seconds worth of AWFUL side effects like a$$-leakage, your head falls off, ya fart out your nose, etc.,.

Eg, could you please change your language? It's getting quite annoying.
Thank you.

[Enviro Girl]

People that have gone out of their way to be rude to me since Day 1: You need to be researching and quoting the works of Emily Post vs. using your time to stalk my every keystroke and nitpick.

Just do what I do when you post, in order to keep the peace here - it's the page down button, just scroll on by...

Kastinka, if you need any research help from me (your request below - when I informed you of Agrobacterium Tumifaciens/Candida poll thread), ya better start any questions w/a full blown apology to me, KC and my ND and take down any trash you posted on them on this and any other forum.

I saw you post you're 'looking into naturopathy'. Why - so you can better rudely libel its U.S. industry leaders?!

Originally Posted by Katinka

Eg, could you please change your language? It's getting quite annoying.
Thank you.

Originally Posted by Katinka

Interesting EG, we've never heard of it. Tell us more....

[Katinka]

All I have to say is: watch your mouth!

[Enviro Girl]

Baraka, thanks for the Monty Python! Haaa! I had an English comp. teacher in HS that used to show us clips!

[Baraka Obam]

Please just do not say NEE!!!!!!! LOL!!!!