My friend... Thalassemia

[Seasprite]

I originally started looking into Morgs because my friend has been going crazy with ithcing for years! Then I started itching and my friend thought he gave it to me. I didn't believe it.
He thought he had Morgs and thought that I had it also. I didn't believe in Morgs so I tried to learn all I could. I read that most people also had lyme. So I got tested for Lyme to rule it out. And I tested positive! So did my friend.

But here's the thing... He has a genetic disease (did not know this earlier) called Thalassemia. (It is too many red blood cells and mishshapen red blood cells) (and some other features) there are about 4 grades of it (levels of severity) He has a mild form, proably the syndrome vs the full blown disease.

There is a link between people who have T. and a water mold which causes severe itching (and other Morgs symptoms!!) We are hoping we are closer to an answer!!

His (yet another new one) doc is being supportive and also helping us reasearch. I went to an apt with him to make sure he got more tests done, like the CD 57. I am still trying to figure out his number on that. His version of the results is harder to read than mine.

Somewhere I have a link on this.

Good luck everyone, sprite

[Katinka]

Thalassemia
Also called: Cooley's anemia, Mediterranean anemia
If you have thalassemia, your body has problems making hemoglobin, the protein in red blood cells that carries oxygen through your body. When your blood does not carry enough oxygen to the rest of your body, you have anemia.
Thalassemia, a genetic disease, can be mild or severe. Some carriers of the gene have no symptoms. The most common severe form in the United States is a type called Cooley's anemia. It mainly affects people of Mediterranean or Asian ancestry. It usually appears during the first two years of life. Severe thalassemia is treated with blood transfusions and treatment to remove excess iron in the blood.


Katinka

[Baraka Obam]

This is where this plague started for me, I have not seen an Asian morgellons victim yet. Maybe its been there a long long time! Maybe it makes peoples skin yellowish like it did mine!!!

[Seasprite]

Pythium insidiosum is a pathogen that causes disease in both animals and humans. Human infection is rare; however, when it does occur, most patients, especially
those having underlying hemoglobinopathy syndromes, such as thalassemia, exhibit a severe form.

Human infection was first diagnosed in two Thai thalassemic patients with subcutaneous granulomatous lesions and was reported in 1986 ...

The disease may be manifested as a subcutaneous, systemic, vascular, or ophthalmic type. The systemic type usually occurs in thalassemic or leukemic patients.
Most patients have a severe form that resists treatment.

Because of the severe progression of the disease, rapidly sensitive and specific tests are necessary for diagnosis and prognosis monitoring.


Identification of Emerging Human-Pathogenic Pythium insidiosum by Serological and Molecular Assay-Based Methods -- Vanittanakom et al. 42 (9): 3970 -- Journal of Clinical Microbiology

Pythium insidiosum is a pathogen that causes disease in both animals and humans. Human infection is rare; however, when it does occur, most patients, especially
those having underlying hemoglobinopathy syndromes, such as thalassemia, exhibit a severe form. We identified four isolates of P. insidiosum. Two were
recovered from tissue biopsy specimens from thalassemic and leukemic patients, one was derived from brain tissue from a thalassemic patient, and another
was isolated from a corneal ulcer from a fourth patient. Western blotting and an enzyme-linked immunosorbent assay (ELISA) were performed with a serum
sample derived from one thalassemic patient. The methods used to identify the P. insidiosum isolates were based on morphology, nucleic acid sequencing,
and a PCR assay. To confirm the identification, portions of the 18S rRNA genes of these four isolates were sequenced. The sequences were shown to be homologous
to previously described P. insidiosum DNA sequences. In addition, PCR amplification of the internal transcribed spacer region specific for P. insidiosum
was positive for all four isolates. The ELISA with the serum sample from the thalassemic patient gave a positive result from a serum dilution of 1:800.
Finally, Western immunoblotting with this serum sample showed positive immunoglobulin G recognition for proteins of 110, 73, 56, 42 to 35, 30 to 28, 26,
and 23 kDa. The results of this study show that both molecularly based diagnostic and serodiagnostic techniques are useful for the rapid identification
of human pythiosis. The predominant antigens recognized by Western blotting may be useful in the development of a more sensitive and specific diagnostic
tool for this disease.

....................

Thalassemia - Wikipedia, the free encyclopedia

Thalassemia (from ?a?assa, thalassa, sea + a?µa, haima, blood; British spelling, "thalassaemia") is an inherited autosomal recessive blood disease. In thalassemia,
the genetic defect results in reduced rate of synthesis of one of the globin chains that make up hemoglobin. Reduced synthesis of one of the globin chains
can cause the formation of abnormal hemoglobin molecules, thus causing anemia, the characteristic presenting symptom of the thalassemias.

Thalassemia is a quantitative problem of too few globins synthesized, whereas sickle-cell anemia (a hemoglobinopathy) is a qualitative problem of synthesis
of an incorrectly functioning globin. Thalassemias usually result in underproduction of normal globin proteins, often through mutations in regulatory genes.
Hemoglobinopathies imply structural abnormalities in the globin proteins themselves.[1]
The two conditions may overlap, however, since some conditions which cause abnormalities in globin proteins (hemoglobinopathy) also affect their production
(thalassemia). Thus, some thalassemias are hemoglobinopathies, but most are not. Either or both of these conditions may cause anemia.

The disease is particularly prevalent among Mediterranean people, and this geographical association was responsible for its naming: Thalassa (???assa) is
Greek for the sea, Haema (a?µa) is Greek for blood. In Europe, the highest concentrations of the disease are found in Greece and in parts of Italy, in
particular, Southern Italy and the lower Po valley. The major Mediterranean islands (except the Balearics) such as Sicily, Sardinia, Malta, Corsica, Cyprus
and Crete are heavily affected in particular. Other Mediterranean people, as well as those in the vicinity of the Mediterranean, also have high rates of
thalassemia, including Middle Easterners and North Africans. Far from the Mediterranean, South Asians are also affected, with the world's highest concentration
of carriers (18% of the population) being in the Maldives.

[Seasprite]

The reason I am submitting all this, is that people also need to rule out all other types of problems before jumping on the Morgellon's band wagon. Maybe it is a KNOWN pathogen affecting a person, just no one has put the pieces of the puzzle together.

I am trying to figure out what the vector of the above pathogen is, and I think it's a water borne mold. I still have to do some reasearch, or if you find it before I do, please post.

Thanks everyone for your support.

-sprite

[Kritters]

I agree with you Sprite.

In fact, I am getting so tired of all these freaking pathogens we are finding. How do we know they aren't all the same in different stages found by different people naming them?

I think I might have to take a break.

xoKritts

[sarothra]

Originally Posted by Kritters

I agree with you Sprite.

In fact, I am getting so tired of all these freaking pathogens we are finding. How do we know they aren't all the same in different stages found by different people naming them?

I think I might have to take a break.

xoKritts

I'm 100% with you on that Krits! I still think we have three "Morgellon" pathogens - if you search the human body one will always find other "stuff" lurking, opportunistic and normal flora (and fauna). It's driving me crazy all the stuff people keep coming up with.

There is no consensus that way, just confusion.

Everything I have researched - and some others - points to the nemotode/fungus/bacteria trio.

It makes sense. It explains everything EXCEPT why they see these fibers are "non-biological" - and I think that is explained by the fact that they feed these nematodes a diet of plastics and other polymers mixed with animal fat. I'm sure the "outer" layer just would look "other-worldly".

My next step is to try to find a university that has a Nematology Dept. and send one of the "juvenile" (moving) fibers to them to see if they can identify it.

I don't have any of the colored fibers or I'd send them too.

Will keep everyone informed.

sar

[Kritters]

Thank you Saro....

I know you are an educated researcher and really appreciate your advanced knowledge and tenacity in revealing this crap.

I'm rootin' for ya.

xoxo
Kritts

[violet]

Originally Posted by Seasprite

I originally started looking into Morgs because my friend has been going crazy with ithcing for years! Then I started itching and my friend thought he gave it to me. I didn't believe it.
He thought he had Morgs and thought that I had it also. I didn't believe in Morgs so I tried to learn all I could. I read that most people also had lyme. So I got tested for Lyme to rule it out. And I tested positive! So did my friend.

But here's the thing... He has a genetic disease (did not know this earlier) called Thalassemia. (It is too many red blood cells and mishshapen red blood cells) (and some other features) there are about 4 grades of it (levels of severity) He has a mild form, proably the syndrome vs the full blown disease.

There is a link between people who have T. and a water mold which causes severe itching (and other Morgs symptoms!!) We are hoping we are closer to an answer!!

His (yet another new one) doc is being supportive and also helping us reasearch. I went to an apt with him to make sure he got more tests done, like the CD 57. I am still trying to figure out his number on that. His version of the results is harder to read than mine.

Somewhere I have a link on this.

Good luck everyone, sprite

Interesting, and I have a vested interest since I also have a condition with too many red blood cells--polycythemia vera. I'll be interested in what the doc there finds!