Garth Nicholson: LB-Morgellons Post by Skizit

[tcmgpt13]

I hope it's okay to copy and post this information here on MDR (with proper credits) which was originally posted on Lymebusters-Morgellons by skizit. This is such interesting information and it is the result of this enterprising poster at LB-M writing to Dr. Nicholson about Morgellons and receiving a detailed response from him. No wonder we are having a hard time getting well and you will understand why from reading his email. Since he has good credentials hopefully his thoughts on this issue will help us, if not now sometime in the future. His mention of another anti-parasitic drug I have not heard of is interesting too. He mentions why it is hard to get doctors to experiment with this and other drugs to treat M. He says what I have been suspecting for some time and that is that there is most likely no one easily identified organism responsible for what is better called the Morgellons syndrome. For those interested and who have not already seen it, Nicholson's protocol is posted on MDR where made suggestions for treatments and supplements which might help control Morgellons symptoms (from at least a couple years back). This information may also be found on Nicholson's own website:

Topic: Dr. Nicholson's comments on Morgellons (Read 98 times) skizit Ultimate Member ***** member is offline

Joined: Jul 2010 Posts: 622

Nicholson's comments on Morgellons

« Thread Started Yesterday at 3:06pm » I contacted Dr. Nicholson, hoping he could help me with some of the problems in Morgellons. He does not have training in synthetic biology so he is looking for answers in what he knows. He so kindly replied with the following:

Dear SkizitGesture;

Unfortunately, I do not know of someone with the broad background necessary to crack this problem. It does have features of existing diseases, which I presume is caused because of multiple infections that go along with the Morgellons. Thus we can see elements of Lyme Borrelia, Mycoplasma and other microorganisms that could cause some of the systemic signs and symptoms, but this does not explain the extruded fibers and hook-like structures found on skin and other signs and symptoms that to me suggest a subcutaneous parasite, one that may have some elements of insect origin (because of the chitinous nature of some of the extrusions). This is much more complex than the problem of Gulf War Illness that we previously worked on (see Project Day Lily),

From what I know, such chimeric creatures could have been created using elements of genetic engineering plus old-fashioned combinations in culture, but what relationship this could have to Morgellons remains elusive.

We do know the following from patients that we have been in contact with over the last few years and from their responses to advice that we have tried to give them. First, there are elements of bacterial infections in Morgellons. In some cases they can be identified (such as the microorganisms listed above) and treated with appropriate antibiotics, but that is only part of the equation, and although helpful, this does not completely solve the problem.

Second, an important structural element of Morgellons appears to be biofilm, a mainly polysaccharide matrix used for survival, protection from host response and movement of some complex families of microorganisms and parasites. When Morgellons patients are given some very effective biomatrix-busters, such as Detoxamin, they have tremendous Herxheimer Reactions, which one might expect if biomatrix was an important element of the process. Parasites often extrude such matrix material to protect themselves from host responses and to provide a suitable microenvironment for their survival, movement and growth. Breaking down the biofilm matrix, I believe, is one part of solving the problem.

Third, anti-parasite drugs, such as Allnia (nitrazoxanide) or other drugs, might be effective, but only if used in combination with antibiotics, biofilm busters and immune support.

I have tried to get treating physicians to try combinations of antibiotics plus anti-parasite drugs along with the biofilm busters, but none seem to be brave enough to try this without supporting lab evidence, which is difficult to come by.

While it is relatively routine to find, for example, single bacterial, viral or fungal contaminants of foods, finding complex mixtures of organisms in skin samples of Morgellons has been difficult. What I believe is needed is to put together a team of microbiologists, parasitologists, biochemists and pathologists to work together on this problem, but no one seems to have the resources to do this.

Finally, I do not believe that this disease is caused by delusion or hysteria. i believe that it is a real problem that will eventually be identified, and appropriate treatments will be forthcoming. But the problem won't be solved by taking simplistic approaches and assuming that this is a simple problem containing one simple element that will eventually be identified.

Prof. Garth Nicolson (Professor Emeritus of Laboratory Medicine) The Institute for Molecular Medicine

« Last Edit: Yesterday at 3:10pm by skizit »

[sammy]

very imformative post tcm. sammy

[Janice]

Sure looks like saponins would be of great help fighting the bio film.



C. albicans hyphae and biofilm formation were also disrupted in the presence of these natural products.

[Bustercat]

Thanks so much for posting this! I think the guy nailed it on the head with the matrix. Biomatrix busters is such a good terminolgy. For me fighting the biofilm has been an elusive undertaking. This disease is so smart, it takes me some time to catch the new offensive move. I have used time lately as a tool, trying not to do the same thing in the same way, has been benifical.

A combination of antbiotcs, plus anti-parisite drugs, and biofilm busters, with immune support sounds like a great idea. Then the four specialist, microbiologist, parasitologists, biochemist, and pathologist working together on the whole morgellons, would be a dream. Thanks so much for sharing. Bustercat

[kmar]

Thank you TCM for this very informative letter.

I have always respected Dr. G. Nicholson's input.

Agree, very interesting about the Anti parasitical drug he recommended.

Thank you Dr. Nicholson for all you do!

Kmar

[Janice]

I think I am going to take a copy of this letter to my doc. In doing a little research on the anti parasitic drug, I noticed that it has been used in clinical trials for hep c , which is one of my problems and why I am limited on drugs that I can use for this M.
Thank you for your post, quite informative, excellent find!

[kmar]

Found this for one of the treatments he recommended.

‪Detoxamin Information‬‏ -...

[janhef]

I'm sure this isn't the proper way to "post" but I didn't know how else to do it, so, please excuse me...and, tell me how to?

Does anyone have information regarding the potential for Morgellons to be contagious? I am new to this unfortunate dilemma, and have three daughters that I haven't seen as I don't know if they will contract it...HELP please!

[MeaganM]

Hi Jan and welcome. There is a link where you can introduce yourself and ask any questions you have. There are a lot of great people here who are very helpful.

The contagiousness of Morgellons is a question we would all like to know for sure but unfortunately, there is no exact answer. Some believe it is and some don't. The one thing we all agree on is that it is everywhere in the environment so if someone was going to get it, they would get it whether you are around them or not. I also believe that many people have it and don't know it. The fear of giving it to loved ones is something we all worry about but you have to live a life and like I said, it's everywhere.

I hope this helps.

[marsha]

I'm thrilled to see this post! I, too, plan to copy it. Not only for my doctor, but for my family who don't even know about this yet. Thanks so much!