Biodetection system detects multiple pathogens...simultaneously
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Old December 9th, 2010, 11:29 AM
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Default Biodetection system detects multiple pathogens...simultaneously

Encoded Metallic Nanowires Reveal Bioweapons

Encoded Metallic Nanowires Reveal Bioweapons
August 10, 2006

Fair use excerpt:

When dangerous infectious diseases or biological weapons are suspected, fast help is required. The first step is a reliable, sensitive, and unambiguous, yet also fast and simple, identification of the pathogen; preferably, this test should be carried out on the spot, not in a laboratory.


Portable miniature biodetection systems that can detect multiple pathogens simultaneously would be ideal for this task.

American researchers from Lawrence Livermore National Laboratory led by Jeffrey Tok, in collaboration
with groups at Stanford University, University of California at Davis, and Oxonica Inc
....

end excerpt
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Last edited by Venetia; December 9th, 2010 at 11:41 AM. Reason: added defining word
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Old December 9th, 2010, 12:05 PM
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Default Oxford & Stanford created GM Moths & detection system

The irony of the above invention, IMO, is the fact that the same company is involved that brought us
the GM Moth.

Recall this?:

GENETICALLY MODIFIED TO KILL ITS OWN; Deadly fly to aid farm crops. - Free Online Library

Excerpt:

Dr Alphey's experiments on the harmless Drosophila Drosophila: see fruit fly. drosophila

Any member of about 1,000 species in the dipteran genus Drosophila, commonly known as fruit flies but also called vinegar flies. Some species, particularly D. fly have proved successful and the first pest on the hitlist is the cotton-eating bollworm bollworm, name for the larvae of two different moths. The pink bollworm is a serious pest of cotton, and the corn earworm, or cotton bollworm, attacks cotton, corn, and other crops. larvae.

His American colleagues will next month release a swarm of bollworm moths in Arizona modified to glow in the dark.

Researchers will monitor their breeding patterns and movement before deciding whether to breed and release killer bollworm moths.

end excerpt



Here is what one person had to say about the above:

GM Files: GMIs – Genetically Modified Insects


GM Files: GMIs – Genetically Modified Insects

Excerpt:

I am nearly speechless by the stupidity and ill-conceived arrogance of industry scientists who are playing havoc with my world and yours.


end excerpt

(( me too, Rima ))


Oxonica Inc in the above post has a UK and US 'branch'

Us (nano division) Stanford U

Oxonica Inc.

Oxonica Inc. (( Note the url name is biochip net dot com ))

UK - Oxford U

Oxonica - Leaders in nanotechnology (GM insects too)


See more on the GM moths:

Calcite in 'M' and in Soda pop? Aspergillus niger too!

Scroll down to this:

US set to unleash genetically engineered insect
---
Scientists Create GM Killer - Moth To Control Pests - Trials Begin
By James Meek - Science Correspondent
The Guardian Latest news, comment and reviews from the Guardian | guardian.co.uk

More:

Scientists create GM killer mother
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Last edited by Venetia; December 9th, 2010 at 04:38 PM.
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Old December 9th, 2010, 12:30 PM
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Default Water purification systems from - Oxford innovators...

Not to worry- the same folk that brought the GM insects have found a way to clean our water. Perhaps from contamination from GM insects et al ?

Co-founder Dr David Kelly started H2oinnovation - he is another Oxford affiliate that was, at one time, partners with Luke Alphey (GM moth co-creator)...



H2O INNOVATION - High Performance Water Treatment Solutions - Reverse Osmosis, NF, UF, MF, membrane systems, water treatment, wastewater, MBR, RO

Nouvelles

Thursday, October 21, 2010
H2O Innovation ranked 108th Fastest Growing Technology Company in North America on Deloitte’s 2010 Technology Fast 500™


Microbial Solutions Board Members

Dr DAVID KELLY: NON-EXECUTIVE DIRECTOR

Fair use excerpt:

David Kelly is co-founder and CEO of H2O Venture Partners. He was cofounder of Oxitec, an Oxford University spinout in the agri-biotech sector, and was Director of Business Development from its foundation in 2002 until 2006, when he left to establish H2O Venture Partners. H2O is invested in Microbial Solutions, and brings to the Company a team of technically and commercially experienced professionals including engineers and life scientists. David has an academic background in microbiology, and before moving into industry was a Pembroke College Lecturer and Research Fellow at Oxford University.
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Old December 9th, 2010, 12:43 PM
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From inspiration to product creation - University of Oxford

Putting research into practice

Fair use excerpt:

In 1994, molecular geneticist Dr Luke Alphey realised that he could turn the techniques learnt in his fundamental studies on Drosophila flies to the control of pest insects, by using genetics to produce sterile insects. Preventing reproduction by mass release of sterile insects reduces insect numbers without the need for insecticides.



In 1999, Dr Alphey took this groundbreaking idea to the University’s wholly-owned technology transfer company, Isis Innovation. The scientific and commercial expertise of its staff enabled him to work through all the stages necessary to turn the idea into reality: first protecting the intellectual property (IP), then, with fellow zoologist Dr David Kelly, finding investors and in 2002 setting up a company. That spin-out company – Oxitec (Oxford Insect Technologies),

end excerpt

More:

ZoomInfo.com
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Old December 9th, 2010, 03:51 PM
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I have to wonder if the answer/s to the Zoonotic disease/emergingdiseases lie/s in the gene-splicing technology per the above GM insects.


Telomerase is Key, IMO

((you have to wonder if they did the splicing in the area of Telomerase with those GM insects?))


Good Morgellons article

Oak Hill Gazette: The community newspaper for Southwest Austin

Excerpt:

Stricker has a theory, but acknowledges a lot of research needs to be conducted to see if his theory is correct. He speculates that agrobacterium, which is found in the soil and also in a high percentage of ticks, is the cause of Morgellons, and that the reason many are co-infected with Lyme is that they may contract Morgellons from the same tick that gave them the Lyme disease.

Furthermore, he notes a very curious finding. Telomerase is an enzyme that ads more DNA to the end of a chromosome after cell division. "Every cell and species has telomerase," said Stricker. "There have been comparative studies of telomerase in different organisms and it's been shown that the telomerase in Lyme and agrobacterium are exactly the same."

end excerpt
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Last edited by Venetia; December 9th, 2010 at 04:21 PM.
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Old December 9th, 2010, 04:20 PM
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Default Lyme disease requires a Targeted drug

Telomerase as relates to Lyme disease...

Tick Borne Disease Radio

ResT - In Layman's Terms | Tick Borne Disease Radio

ResT - In Layman's Terms
Submitted by Tom Carolan on Thu, 02/11/2010 - 18:38

Fair use excerpt:

Do you know who won the 2009 Nobel Prize for Medicine? Three telomerase researchers. Telomeres are the end caps to linear genetic material. Human telomeres are repeating patterns of genetic code that signal the end of a genetic strand. Like bumper strips that signal to a driver the end of the road is approaching. The shortening of telomere length has been linked to the aging process and increase risk of cancer. Antioxidants are hyped as a way to keep telomeres from shortening with age. But not all telomeres are built the same, there exist a type of telomere called a "hairpin telomere." Insted of bumper strips of genetic code that signal the end of the linear segment there is a hairpin turn (covalently closed) that caps the end of the double sided helical strand. This forms a very clear end point for the linear segment but imposes a new challenge during genetic replication.

end

Scroll down to this:

TelomerASEs are the class of proteins that form telomeres during the genetic replication process. The telomerase responsible for creating hairpin telomeres is called a Telomere Resolvase aka ResT and is the focus of this article. Before proceeding let's step back, other than the Nobel prize money why should you care about this?

Because ResT is found in some viruses and bacteria, most notably Borrelia Burgdorferi (Bb), the causative agent of Lyme Disease. If the process of telomere resolution could be inhibited using a drug you could discover an effective and very specific treatment for Lyme Disease. It would be specific to Bb because human telomeres are completely different from Bb telomeres. Since the drug would not be a broad range antibiotic it could safely be taken without spreading bacterial resistance. Lyme Disease patients often take prolonged courses of the most potent antibiotics (sometimes without good results - but that is a different story...). This spreads drug resistance and causes many unintended consequences like fungal infections and organ loss. Having a targeted drug is better for patients and everyone else.

end excerpts
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Last edited by Venetia; December 9th, 2010 at 04:35 PM.
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Old December 9th, 2010, 04:55 PM
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I am finding only loop references to what Stricker has said about agrobacterium and lyme having the same telemerases. He says he said he says he said. LOL. Anyway here's old (admittedly) research which says something a bit different and connects lyme a similar structure and sequence of a eukaryotic virus (though there is still mention of crossing over kingdoms to achieve this). I still have not found any links to actual research to back up what Stricker says regarding linkage of Borrelia burgdorferi and agrobacterium telomerases:

J Bacteriol. 1991 Nov;173(22):7233-9.
Linear plasmids of Borrelia burgdorferi have a telomeric structure and sequence similar to those of a eukaryotic virus.

Hinnebusch J, Barbour AG.
Department of Microbiology, University of Texas Health Science Center, San Antonio 78284-7758.
Abstract

Spirochetes of the genus Borrelia have double-stranded linear plasmids with covalently closed ends. The physical nature of the terminal connections was determined for the 16-kb linear plasmid of the B31 strain of the Lyme disease agent Borrelia burgdorferi. Native telomeric fragments representing the left and right ends of this plasmid were isolated and subjected to Maxam-Gilbert sequence analysis. At the plasmid ends the two DNA strands formed an uninterrupted, perfectly palindromic, AT-rich sequence. This Borrelia linear plasmid consisted of a continuous polynucleotide chain that is fully base paired except for short single-stranded hairpin loops at each end. The left and right telomeres of the 16-kb plasmid were identical for 16 of the first 19 nucleotide positions and constituted an inverted terminal repeat with respect to each other. The left telomere of the 49-kb plasmid of strain B31 was identical to the corresponding telomere of the 16-kb plasmid. Different-sized plasmids of other strains of B. burgdorferi also contained sequences homologous to the left end of the 16-kb plasmid. When the borrelia telomeres were compared with telomeric sequences of other linear double-stranded DNA replicons, sequence similarities were noted with poxviruses and particularly with the iridovirus agent of African swine fever. The latter virus and a Borrelia sp. share the same tick vector. These findings suggest that the novel linear plasmids of Borrelia originated through a horizontal genetic transfer across kingdoms.


PMID: 1938918 [PubMed - indexed for MEDLINE]PMCID: PMC209230

You might want to read a post I made a couple years ago when I first thought about iridoviruses due to the bad fish I ate right before getting violently ill with Morgellons. I learned from research that farmed grouper (the fish I ate) was becoming ill with this virus. So have amphibians worldwide and now maybe us as well:

Virus, Fish and Morgellons? (permalink 1)

Quote:
Originally Posted by Venetia View Post
I have to wonder if the answer/s to the Zoonotic disease/emergingdiseases lie/s in the gene-splicing technology per the above GM insects.


Telomerase is Key, IMO

((you have to wonder if they did the splicing in the area of Telomerase with those GM insects?))


Good Morgellons article

Oak Hill Gazette: The community newspaper for Southwest Austin

Excerpt:

Stricker has a theory, but acknowledges a lot of research needs to be conducted to see if his theory is correct. He speculates that agrobacterium, which is found in the soil and also in a high percentage of ticks, is the cause of Morgellons, and that the reason many are co-infected with Lyme is that they may contract Morgellons from the same tick that gave them the Lyme disease.

Furthermore, he notes a very curious finding. Telomerase is an enzyme that ads more DNA to the end of a chromosome after cell division. "Every cell and species has telomerase," said Stricker. "There have been comparative studies of telomerase in different organisms and it's been shown that the telomerase in Lyme and agrobacterium are exactly the same."

end excerpt
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Last edited by tcmgpt13; December 9th, 2010 at 04:58 PM.
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Old December 9th, 2010, 05:36 PM
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Default Lyme has 19 unique hairpin telomeres

Thanks for that info TCM!

I find this of interest in your cited material;

These findings suggest that the novel linear plasmids of Borrelia originated through a horizontal genetic transfer across kingdoms.

Also agree with you about the fish and I'm sorry you got so sick from the grouper. I don't doubt that fish is contaminated with various bacteria, viruses and a variety of heavy metals such as mercury and the remediation products for oil spills such as Geobacter that has the additional quality of eating metal
and transfer electrons:

Geobacter Project - Home


Geobacter species also have the ability to transfer electrons onto the surface of electrodes. As outlined under the Microbial Fuel Cell link, this has made it possible to design novel microbial fuel cells which can efficiently convert waste organic matter to electricity.

Could be why many complain of electric shocks?

We get quite a wide variety of 'stuff' in our food these days!

What I just learned about the Telomerase per the Dr Stricker quote, is that they have learned that Bb- aka Lyme disease is from this source: (also above post) Tick Borne Disease Radio

See the info about the 3 Telomerase researchers- they won the 2009 Nobel Prize for Medicine for their
work with and discoveries in the area.


ResT - In Layman's Terms | Tick Borne Disease Radio

Excerpt:

Do you know who won the 2009 Nobel Prize for Medicine? Three telomerase researchers. Telomeres are the end caps to linear genetic material. Human telomeres are repeating patterns of genetic code that signal the end of a genetic strand. Like bumper strips that signal to a driver the end of the road is approaching. The shortening of telomere length has been linked to the aging process and increase risk of cancer. Antioxidants are hyped as a way to keep telomeres from shortening with age. But not all telomeres are built the same, there exist a type of telomere called a "hairpin telomere." Instead of bumper strips of genetic code that signal the end of the linear segment there is a hairpin turn (covalently closed) that caps the end of the double sided helical strand. This forms a very clear end point for the linear segment but imposes a new challenge during genetic replication.


TelomerASEs are the class of proteins that form telomeres during the genetic replication process. The telomerase responsible for creating hairpin telomeres is called a Telomere Resolvase aka ResT and is the focus of this article. Before proceeding let's step back, other than the Nobel prize money why should you care about this? Because ResT is found in some viruses and bacteria, most notably Borrelia Burgdorferi (Bb), the causative agent of Lyme Disease. If the process of telomere resolution could be inhibited using a drug you could discover an effective and very specific treatment for Lyme Disease. It would be specific to Bb because human telomeres are completely different from Bb telomeres. Since the drug would not be a broad range antibiotic it could safely be taken without spreading bacterial resistance. Lyme Disease patients often take prolonged courses of the most potent antibiotics (sometimes without good results - but that is a different story...). This spreads drug resistance and causes many unintended consequences like fungal infections and organ loss. Having a targeted drug is better for patients and everyone else.

end excerpt

So basically, this is new research. And while Dr Sticker used the term Telomerase it is actually a type of Telomerase - ResT.

I don't know that Dr Stricker knew about the ResT when he made that comment but he was in the ballpark.

What is interesting to me is that this information is stating that ResT is unique so I am wondering how it could be the same as Agrobacterium ti... unless Agro was engineered to be the same as Bb ?

That would be a cruel joke on mankind, eh?

Double whammy.


The above info goes on to state that there are 19 unique hairpin telomeres found on the plasmids and chromosome of Bb and they are grouped into 3 types. Each type share conserved code and experiments have distinguished between the three telomere types.

So, again, my question would be is Agrobacterium the same? I don't know- will have to research and I think that info will be hard to locate.

~V~
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Last edited by Venetia; December 9th, 2010 at 06:26 PM.
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Old December 9th, 2010, 09:23 PM
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Just quickly skimmed this thread, and only want to point out that viruses are not cells - "sequence of a eukaryotic virus " - from TCM's post.
They need to invade cells in order to survive and replicate.

SS
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Old December 9th, 2010, 09:56 PM
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Quote:
Originally Posted by Sadsack View Post
Just quickly skimmed this thread, and only want to point out that viruses are not cells - "sequence of a eukaryotic virus " - from TCM's post.
They need to invade cells in order to survive and replicate.

SS
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