HUMIRA (adalimumab)

[Kritters]

I'm putting this out here because it's a drug for SO MANY autoimmune diseases. I just glossed over it, but I hope some of you will look into it as I will.

Humira (Adalimumab) Drug Information: Uses, Side Effects, Drug Interactions and Warnings at RxList

They SO already know ALL of what micro-organisms can do and do. That's how they come up with medication that makes them trillions of bucks.

What caught my attention is how taking this drug may introduce TB. Now, why would that be?

Another thought is, how would they know how to treat these diseases if they didn't know what organism is actually causing them? Not just one....many.

This stuff just blows me away. grrrrr.

Kritts

[Sadsack]

Kritts -
Drugs like Humira for "autoimmune" diseases supress the immune system, on the theory that the immume system is that is responsible for the illness. Knock it down, you knock down the disease. Unfortunately, the immune system is what protects us against pathogens, including minute exposures to TB.
I was on immune-supression meds for three months and stopped them two years ago when I became very ill with "something" that I couldn't get over. The biting started shortly after.
SS

[Biocentric]

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[Kritters]

Okay....here's what I'm getting...rudimentary as it is.....

I realize that the inflammation is caused by immune cells rushing in to fight infection. That's why the inflammation is there in the first place.

What I've read so far about inflammation and disease is that they are not seeing the forest for the trees. It must be my elementary, non-scientific mind, but.....what is happening, it seems, is that they are attributing the levels of C-Reactive protein (CRP) to determine disease or risk of disease, and are ignoring the fact that pathogens are attracting the immune response. Is it me? I'm writing this in a hurry so it may not make sense yet. So this Humira is thwarting the job of the immune system. I know there are many different dypes of immune substances, and some which are within the inflammatory fluid are doing their jobs. Or not. If the drugs such as humira are minimally effective, there still can be the pathogen in the system, but not to the degree that more immune cells will be brought to the areas/system by the fluid.

So, evidently, whatever the body is sending out to kill/counteract certain pathogens or chemicals, are not the same immune cells needed to kill TB...especially if they are being occupied by keeping the other pathogens/chemicals from multiplying to the point of total destruction.

I'm sure I am missing a ton of relative information and my thoughts are way too simplistic.

Here's something I found which I thought majorly interesting. (speaking of chlamydia pneumonia.........and herpes........as we have been in other threads...)

Inflammation, Heart Disease and Stroke: The Role of C-Reactive Protein
“Inflammation” is the process by which the body responds to injury or an infection. Laboratory evidence and findings from clinical and population studies suggest that inflammation is important in atherosclerosis (ath”er-o-skleh-RO’sis). This is the process in which fatty deposits build up in the inner lining of arteries.
“…………….C-reactive protein (CRP) is one of the acute phase proteins that increase during systemic inflammation. It’s been suggested that testing CRP levels in the blood may be an additional way to assess cardiovascular disease risk…….”


What causes low-grade inflammation?
The major injurious factors that promote atherogenesis — cigarette smoking, hypertension, atherogenic lipoproteins, and hyperglycemia — are well established. These risk factors give rise to a variety of noxious stimuli that cause the release of chemicals and the activation of cells involved in the inflammatory process. These events are thought to contribute not only to the formation of plaque but may also contribute to its disruption resulting in the formation of a blood clot. Thus, virtually every step in atherogenesis is believed to involve substances involved in the inflammatory response and cells that are characteristic of inflammation.
In addition, there is also research that indicates an infection — possibly one caused by a bacteria or a virus — might contribute to or even cause atherosclerosis. The infectious bacteria, Chlamydia pneumoniae (klah-MID'e-ah nu-MO'ne-i), has been shown to have a significant association to atherosclerotic plaque. The herpes simplex virus has also been proposed as an initial inflammatory infectious agent in atherosclerosis.
The notion that chronic infection can lead to unsuspected disease isn't foreign to most doctors. For example, bacterial infection with Helicobacter pylori is now known to be the major cause of stomach ulcers. The treatment for this condition now routinely includes antibiotic therapy.
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Okay....they KNOW these organisms cause disease. Do they know that replacing some of the vitamins and minerals these pathogens use to live and multiply can possibly reverse the disease, or help the immune system do so? So, they make cancer, for instance, seem like this enigmatic disease and they JUST CAN'T FIND THE FREAKING CURE. Well, Dr. Simoncini and other brilliant and brave researchers who were kicked out of practicing medicine HAVE FOUND the cures.

Well, sooner or later, BIG PHARMA.....INSURANCE INDUSTRY.....HERDED MEDICAL DOCTORS....you are going to have to face the music and admit you have been duping sick people all along. The truth WILL come out.

Grrrr. again.

Kritters

[Sadsack]

Bio -
Yeah, supresses the immune response.
SS