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Cyclic peptides yield promising antimicrobial results : The Lancet Infectious Diseases

Cyclic peptides yield promising antimicrobial results

"Researchers at The Scripps Research Institute (La Jolla, CA, USA) reported in Nature recently that cyclic D,L-α-peptides can rapidly kill bacteria by forming “hole-punching” tubular nano-structures. “These peptides self-assemble into hollow tubes in response to their environment”, and because they each carry at least one basic aminoacid, they have an enhanced specificity towards negatively charged bacterial membranes compared with mammalian membranes”, explains lead author Reza Ghadiri. Animal e ..."