Elsevier DRUG RESISTANCE AMONG MALARIA AND OTHER PARASITES Lawrence M. Barat, MD, MPH
*,
Peter B. Bloland, DVM, MPVM
*
Parasitic infections are among the most common infectious diseases worldwide.
Intestinal parasites, such as Ascaris, hookworms, and Trichuris, infect many hundreds of millions of people. Malaria is responsible for between 300 and 500 million clinical cases and 1.5 to 2.5 million deaths each year. More than 200 million people are infected with
Schistosoma and another 200 million are infected with
Giardia.
The greatest public health threat posed by drug resistance among parasites is from malaria, and most of this article is devoted to discussing issues related to the development, spread, and impact of drug resistant malaria.
Concern also is growing, however, about the development of drug resistance among non-malarial parasites; we discuss metronidazole resistance in both Giardia and Trichomonas, and the possibility of ivermectin resistance in human filariasis.
© 1997 W. B. Saunders Company. Published by Elsevier Inc. All rights reserved.
2many, hopefully this is an appropriate place to post this. I wonder if the fact that filarial parasites are probably close to all being infected with agrobacterium has anything to do with them being resistant to Ivermectin, which I know alot of people on this forum and other friends that I have is their drug of choice to rid themselves of these nematodes?
Niecy
