Thank you toomanyfibers!! I have a hard finding things, and that was a great help. I am very unsure about taking this medication, my allergy to penicillin is respritory, and they didn't give me anything to counteract it if I did have a reaction. I think I will give my doc a call and see if he can use something else in it's place. Thank you again for your help............xxxxxxxNiecy
DRUG
INTERACTIONS: Patients who are allergic to penicillin may (theoretically have a sensitivity to penicillamine), but this is not common. (Penicillamine can increase the requirement for vitamin B6 (pyridoxine) and supplementation is advised.) Penicillamine should not be taken by patients who are also taking gold (Myochrysine, Ridaura, Solganal), antimalarial (Plaquenil), phenylbutazone (Butazolidine), or cytotoxic drugs (Cytoxan, Imuran, Rheumatrex)( because of similar bone marrow and kidney risks).( Penicillamine can weaken the protein (collagen) that is used to form body tissues.) Therefore, it is advised to reduce the dose when surgery is considered and resume full dose after the wound has healed.
The effectiveness of penicillamine for treating arthritis in children has not been established.
PREGNANCY: Penicillamine should not be taken by pregnant women with rheumatoid arthritis. Women with rheumatoid arthritis in whom pregnancy is suspected should discontinue penicillamine.
SIDE EFFECTS: Penicillamine can cause rashes early in treatment which usually resolve within days of discontinuing the drug. A late rash, seen after 6 months of treatment, may take weeks to disappear. Rashes can be associated with itching, which can often be controlled by simply adding antihistamine medication. Rashes associated with fever and joint pain usually require discontinuing penicillamine. It can also cause loss of appetite, nausea, abdominal pain, and loss of the sense of taste.
Penicillamine can cause( bone marrow suppression )and (serious kidney disease). All patients who take penicillamine require regular blood and urine testing for monitoring.
Penicillamine has an( unusual risk of inducing immune-related diseases, such as systemic lupus erythematosus, polymyositis, Goodpasture's syndrome and myasthenia gravis.)
That's some pretty serious side effects!! Don't you think?
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Originally Posted by 2manyfibers Hey Niecy - I saw your question about penicillamine and penicillin and thought I would try to help a bit. Penicillimine is a metabolite of penicillin (which basically means it's derived from it and only specific molecules of the penicillin are used to create it) and it has no antibiotic properties although it does suppress the immune system as an antibiotic does. It is often used to treat rheumatoid arthritis. From what I could find people with an allergy to penicillin should use caution when taking penicillamine although it doesn't appear that people with an allergy to penicillin are always allergic to penicillamine. So I guess the bottom line would be to use caution with it if you do take it - watch for the symptoms of an allergic reaction with your first dose or two would be the best way to approach it I would guess. Hope this helps. Here's some specific information from the following website (and there is more information available there too - you can do an internet search on "penicillamine allergy" and find a good bit of information): http://www.emedicinehealth.com/under...s/page8_em.htm
Side effects: Penicillamine must be used with caution in individuals who are allergic to penicillin or who have kidney impairment. Penicillamine may decrease blood cell counts. Common side effects include nausea, vomiting, stomach pain, and diarrhea. Sense of taste may be impaired. Contact a doctor if any of the following occur:
Wheezing or breathing troubles
Unexplained fever
Sore throat
Unusual bleeding or bruising
Vision changes
Rash
Itching |